Volume 3,Issue 7
结肠支架置入术治疗老年左半结直肠癌伴梗阻——临床应用效果分析
目的 探究结肠支架置入术在老年左半结直肠癌伴梗阻患者中应用的效果。方法 选择2022.01-2024.06在东台市人民医院因左半结直肠癌住院的患者行结肠支架置入术治疗,评价结肠支架置入术的效果及术后并发症及6个月生存率。结果 16位患者均成功置入结肠支架,其中2名患者支架置入术后出血;1名患者出现支架移位;10例患者术后选择了外科手术进一步治疗,未行外科手术的患者中有2例选择了化疗及免疫治疗。术后6个月生存率87.5%。结论 结肠支架置入术可迅速改善老年左半结直肠癌伴梗阻患者的梗阻症状,疗效确切、并发症少,提高肿瘤Ⅰ期切除率,为进一步治疗提供了可能。
[1]葛均波,王辰,王建安主编.内科学 10 版[M].北京:人民卫生出版社,2024. 7,395-397.
[2]郑树.结直肠肿瘤基础研究与临床实践[M].北京:人民卫生出版社,2006.
[3]迟宝欣,常志恒 等.结肠支架联合外科手术治疗急性梗阻性结直肠癌的效果.中国医学创新[J],2025,22(1):25-30.
[4]束庆文,谢玉珍 等.结肠镜联合X线行扩张与内支架置入治疗左半结肠恶性狭窄与梗阻的价值[J].蚌埠医学院学报,2012,37(2):208-209,212.
[5]邹瞭南,万进 等.结肠内支架置入联合腹腔镜手术治疗急性左半结肠恶性梗阻[J].中华胃肠外科杂志,2011,14(11):903-904.
[6]黄新香,郑金辉 等.结肠支架在左半结肠恶性梗阻中的应用价值.深圳中西医结合杂志[J],2022,32(19):104-106.
[7]李鹏莉,石定.支架置入后择期手术与急诊手术治疗急性右半结肠恶性梗阻临床疗效比较.实用医学杂志[J],2022,38(1):79-84.
[8]Imbulgoda A, MacLean A, Heine J, et al. Colonic perforation with intraluminal stents and bevacizumab in advanced colorectal cancer: retrospective case series and litera
ture review. Can J Surg, 2015; 58(3):167-171.
[9]van Hooft JE, Veld JV, Arnold D, et al. Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE)
Guideline - Update 2020. Endoscopy, 2020; 52(5):389-407.
[10]叶乾礼.延长内镜下结肠支架置入术与限期手术的时间间隔对梗阻性左半结肠癌患者预后的影响.吉林医学[J],2023,44(3):678-681.
[11]MU C,CHEN L.A retrospective evaluation of short-term results from colonic stenting as a bridge to elective surgery versus emergency surgery for malignant colonic
obstruction[J].Scientific Reports,2023,13(1):1600.
[12]TAN C J,DASARI B V M,CARDINER K.Systematic review and meta-analysis of randomized clinical trials of self-expanding metallic stents as a bridge to surgery
versus emergency surgery for malignant left-sided large bowel obstruction[J].British Journal of Surgery,2012,99(4):469-476.
[13]YOON J, KWON SH, LEE CK, et al.Radiologic placement of uncovered stents for the treatment of malignant colonic obstruction proximal to the
descending colon[J]. Cardiovasc Intervent Radiol,2017,40(1):99-105.
[14]van Hooft JE, van Halsema EE, Vanbiervliet G, et al. Self-expadable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal
Endoscopy (ESGE) clinical guideline. Endoscopy, 2014; 46(11): 990-1053.
[15]Cirocchi R, Arezzo A, Sapienza P, et al. Current status of the self-expandable metal stent as a bridge to surgery versus emergency surgery in colorectal cancer: Results
from an updated systematic review and meta-analysis of the literature. Medicina (Kaunas), 2021; 57(3):268.