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Volume 3,Issue 7

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20 May 2025

乳腺癌肺转移瘤合并原发性肺癌:一例病例报道

嘉维 王1 智超 孙1 玲 王3 丹 陈2 春东 顾1,4 士磊 赵1,4
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1 大连医科大学附属第一医院胸外科, 中国
2 大连医科大学附属第一医院病理科, 中国
3 大连医科大学附属第一医院肿瘤科, 中国
4 大连市肺癌诊疗基地, 中国
MRP 2025 , 3(5), 19–22; https://doi.org/10.61369/MRP.2025050010
© 2025 by the Author. Licensee Art and Design, USA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

在临床实践中乳腺癌肺转移瘤同时合并原发性肺癌的情况极为罕见,目前治疗方式缺乏相应的循证医学证据。本案例报道了一例55岁中年女性患者,既往8年前因“右侧乳腺浸润性导管癌”而接受右侧乳腺癌根治术,术后接受了规范的化放疗和内分泌治疗;今患者因“右肺上叶肿物(两病灶)”而接受3D胸腔镜下右肺上叶切除术联合系统性纵隔内淋巴结清扫术。术后病理学检查显示一病灶为乳腺癌肺转移瘤、另一病灶为肺原发浸润性腺癌。本案例追溯了患者整个诊治过程,综合运用影像、免疫组化和分子病理检测等手段,多维度的鉴别了右肺上叶多个病灶的分子遗传特征及来源,进而能够为临床治疗提供更为精确的指导,优化治疗方案,提高治疗效果。

Keywords
乳腺癌
肺转移瘤
原发性肺癌
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