Volume 3,Issue 2
Fall 2025
脑膜瘤预后相关生物标记物研究进展
脑膜瘤是常见的原发性颅内肿瘤，发病率约占成人颅内肿瘤中的 30%~40%， 多数良性脑膜瘤手术切除后预后良好，但部分恶性脑膜瘤侵袭性强、易复发，治疗难度较大。[1] 目前临床对脑膜瘤预后评估主要依赖于组织学分级、手术切除程度、肿瘤生长部位及大小等传统指标，难以全面反映患者个体差异和肿瘤生物学特性，因此寻找更为精准可靠的预后生物标记物成为脑膜瘤研究重点。近年来，分子生物学技术发展推动了脑膜瘤分子分型与预后生物标记物研究的突破。本文系统综述脑膜瘤预后相关生物标记物的研究进展，探讨其在预后评估、个体化治疗及临床决策中的应用价值，以期为脑膜瘤的临床诊疗提供新的思路。
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