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18 June 2025

Observation on the Clinical Efficacy of Modified Danggui Shaoyao Powder Combined with Acupoint Embedding in the Treatment of “Phlegm-dampness Type” Ovulation Disorder Infertility in PCOS

Hongzhong Li1* Qianru Yu1 Lin Ji1 Jinfeng Yu2 Youping Yang3
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1 People’s Hospital of Yucheng District, Ya’an Second People’s Hospital, Ya’an 625000, Sichuan, China
2 Maternal and Child Health Hospital of Yucheng District, Ya’an 625000, Sichuan, China
3 People’s Hospital of Yingjing County, Ya’an 625000, Sichuan, China
AMCMR 2025 , 1(2), 16–26; https://doi.org/10.61369/AMCMR.202502003
© 2025 by the Author. Licensee Art and Design, USA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Objective: To explore the clinical therapeutic effect of modified Danggui Shaoyao Powder combined with acupoint embedding thread in the treatment of infertility caused by phlegm-dampness type ovulation disorders. Methods: From January 2024 to May 2025, 98 patients with PCOS “phlegm-dampness type” ovulation disorders who met the research conditions were grouped in a 1:1 ratio. The control group (n = 48) was treated with modified Danggui Shaoyao Powder, Letrazole (LE), and metformin. Patients in the experimental group (n = 48) were treated with acupoint embedding on the basis of the above-mentioned medication, and the clinical efficacy of the two groups of patients was compared. Results: The pregnancy rate of patients in the experimental group after treatment was 69.39%, the ovulation rate was 93.88%, and the total effective rate was (93.88%), while that of the control group was only 59.18%, P < 0.05; The scores of blood lipid and insulin resistance in the experimental group after treatment were lower than those in the control group (P < 0.05). After treatment, the levels of acne, acanthosis nigricans, F-G hirsutism and BMI in the experimental group were lower than those in the control group (P < 0.05). After acupoint embedding therapy in the experimental group, the ovarian volume recovered significantly and the number of follicles decreased significantly. During the treatment period, the comparison result of the incidence of side effects between the experimental group and the control group was P > 0.05. Conclusion: In the treatment of PCOS patients with “phlegm-dampness type” ovulation disorders, the use of modified Danggui Shaoyao Powder combined with acupoint thread therapy can increase the pregnancy rate and ovulation rate of patients, improve the clinical symptoms of patients, regulate the volume of the ovary and the number of follicles at the same time, and does not increase the adverse reactions of patients with medication.

Keywords
Addition and subtraction of Angelica Sinensis and Peony Powder
PCOS
Phlegm-dampness type
Ovulation disorder
Funding
Project of Sichuan Provincial Administration of Traditional Chinese Medicine (Project No.: 2024MS462)
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