Volume 1,Issue 3
Study on the Relationship between Distribution of Traditional Chinese Medicine Syndromes and Pathological Changes in Chronic Atrophic Gastritis
Objective: This study aims to investigate the distribution of traditional Chinese medicine (TCM) syndrome types in chronic atrophic gastritis (CAG) and explore the correlation between TCM syndrome types and pathological changes, providing an objective basis for clinical syndrome differentiation and treatment. Methods: A retrospective study was conducted, involving the summary and analysis of medical records from 201 CAG patients who met the inclusion criteria. TCM syndrome differentiation was performed, followed by logistic regression analysis of the relationship between TCM syndrome types and pathological changes in the patients’ gastric mucosa. Results: The distribution of TCM syndrome types among the 201 patients, from highest to lowest, was liver-stomach heat stagnation syndrome, liver-stomach “Qi” stagnation syndrome, spleen-stomach damp-heat syndrome, spleen-stomach weakness syndrome, stomach collaterals stasis syndrome, and stomach “Yin” deficiency syndrome. There was a statistically significant difference in the distribution of intestinal metaplasia among different TCM syndrome types. Compared to the liver-stomach “Qi” stagnation syndrome, the liver-stomach heat stagnation syndrome showed a significant increase in mild intestinal metaplasia (p < 0.05). No statistically significant differences were observed in the distribution of inflammation, activity, glandular atrophy, and dysplasia among different TCM syndrome types. In the correlation analysis between syndrome types and pathological changes, the liver-stomach “Qi” stagnation syndrome was negatively correlated with intestinal metaplasia, while the spleen-stomach damp-heat syndrome was positively correlated with glandular atrophy. The remaining syndrome types showed no correlation with pathological changes. Conclusion: A certain correlation is observed between TCM syndrome types of CAG and pathological changes of gastric mucosa.
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